This gene encodes a member of the LEM family of inner nuclear membrane proteins. The encoded protein functions as a mitotic regulator through postmitotic formation of the nuclear envelope. Mutations in this gene cause morphology defects in the nuclear envelope and BAF hyperphosphorylation. [provided by RefSeq, Mar 2014]
Function
protein binding; protein phosphatase 2A binding; protein phosphatase type 2A regulator activity
Synonyms
ANKLE2; ankyrin repeat and LEM domain containing 2; Lem4; LEMD7; KIAA0692; ankyrin repeat and LEM domain-containing protein 2; LEM domain containing 7; LEM domain-containing protein 4
Citations
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