Human STAMBP peptide

Specificity

Ubiquitously expressed.

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

Belongs to the peptidase M67C family.Contains 1 MPN (JAB/Mov34) domain.

Alternative Names

The JAMM motif is essential for the protease activity.

Purity

70 - 90% by HPLC.

Format

Liquid

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Entrez Gene ID

Antigen Description

Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]

Function

metal ion binding; metallopeptidase activity; protein binding; ubiquitin-specific protease activity;

Synonyms

STAMBP; STAM binding protein; AMSH; MICCAP; STAM-binding protein; endosome-associated ubiquitin isopeptidase; associated molecule with the SH3 domain of STAM;