Specifications
Species Reactivity
Human; Mouse; Rat; Pig; Cow; Horse; Rabbit
Immunogen
KLH conjugated synthetic peptide derived from human ALOX15B/15 Lipoxygenase 2: 13-110/676
Applications
Application Notes
IHC-P: 1:100-500
IHC-F: 1:100-500
IF: 1:100-500
General Notes
This product (Catalog No. CABT-BL4151) is a rabbit-derived IgG polyclonal antibody raised against human ALOX15B, targeting the amino acid region 13–110 of the protein. This antibody exhibits cross-reactivity with ALOX15B from mouse, rat, pig, cow, horse, and rabbit. It has been affinity purified by Protein A. This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described.
CABT-BL4151 is suitable for use in IHC-P (1:100–1:500), IHC-F (1:100–1:500), IF (immunofluorescence) (1:100–1:500) applications.
CABT-BL4151 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
15 LO 2; 15 LOX 2; 15-lipoxygenase 2; 15-LOX-2; 15-LOX-B; ALOX15B; Arachidonate 15 lipoxygenase second type; Arachidonate 15 lipoxygenase type II; Arachidonate 15-lipoxygenase B; Arachidonate 15-lipoxygenase type II; LX15B_HUMAN; ALOX8_MOUSE; Arachidonate 8S-lipoxygenase; 8-LOX; 8S-LOX; 15-lipoxygenase 2; Arachidonate 15-lipoxygenase B; 15-LOX-B
Citations
Publication ()
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