RHA™ anti-19-norandrosterone monoclonal antibody, clone 19NT

Antibody Isotype

IgG

Clone

19NT

Immunogen

19-Norandrosterone [KLH]

Conjugate

Application Notes

Indirect ELISA IC50: 0.2 ppb
Matched pair conjugate available for 19-Norandrosterone antibody:
19-Norandrosterone [BSA](Catalog # DAGA-019B)
19-Norandrosterone [HRP](Catalog # DAGA-017H)

Alternative Names

19-Norandrosterone Antibody

Antigen Description

19-Norandrosterone is a nandrolone and 19-norandrostenedione metabolite. It is created as a byproduct of nandrolone via the 5-alpha reductase enzyme and is on the list of substances prohibited by the World Anti-Doping Agency since it is a detectable metabolite of nandrolone which is an anabolic steroid.[1] Consumption of androstendione products contaminated with traces of 19-norandrostenedione also results in testing positive for nandrolone.[2]

Traces of 19-norandrosterone may be naturally present in human urine. An experiment conducted on athletes showed that after a prolonged intense effort, the 19-norandrosterone concentration can be increased by a factor varying between 2 and 4,[3] but another study failed to replicate the result.[4] Concentration also increases in the urine of female athletes during menstruation.[5] The consumption of edible parts of a non-castrated pig, containing 19-nortestosterone, has been shown to result in the excretion of 19-norandrosterone in the following hours, so athletes should prudently avoid meals composed of pig offal in the hours preceding doping tests.[6] Consumption of boar meat, liver, kidneys and heart also increased 19-norandrosterone output.[7]