a 18 amino acid peptide from near the carboxy-terminus of human ZBP1.
Conjugate
Unconjugated
Target
Alternative Names
ZBP1; Z-DNA binding protein 1; DAI; DLM1; DLM-1; C20orf183; Z-DNA-binding protein 1; DNA-dependent activator of IRFs; DNA-dependent activator of IFN-regulatory factors; tumor stroma and activated macrophage protein DLM-1; DNA-dependent activator of interf
This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Pathway
Cytosolic DNA-sensing pathway; Cytosolic sensors of pathogen-associated DNA; IRF3 mediated activation of type 1 IFN; IRF3-mediated induction of type I IFN; Immune System; Innate Immune System; RIP-mediated NFkB activation via ZBP1; Regulation of innate immune responses to cytosolic DNA
Citations
Publication ()
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COA
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