Anti-ZBP1 monoclonal antibody

Antibody Isotype

IgG1

Species Reactivity

Human

Immunogen

Recombinant fragment: AQAPADPGRE GHLEQRILQV LTEAGSPVKL AQLVKECQAP KRELNQVLYR MKKELKVSLT SPATWCLGGT DPEGEGPAEL ALSSPAKRPQ QHAATIPET, corresponding to N terminal amino acids 2-100 of Human Z DNA binding protein (NP_110403) with a proprietary tag.

Conjugate

Application Notes

WB: 1 - 5 μg/ml; IHC-P: 3 μg/ml;

Alternative Names

ZBP1; Z-DNA binding protein 1; C20orf183, chromosome 20 open reading frame 183; Z-DNA-binding protein 1; DAI; dJ718J7.3; DLM 1; DLM1; DNA dependent activator of IRFs; DNA-dependent activator of IRFs; DNA-dependent activator of IFN-regulatory factors; tum

Entrez Gene ID

UniProt ID

Antigen Description

May play a role in host defense against tumors and pathogens. Binds Z-DNA.

Pathway

Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Cytosolic sensors of pathogen-associated DNA, organism-specific biosystem; DAI mediated induction of type I IFNs, organism-specific biosystem; IRF3 mediated activation of type 1 IFN, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem;