Rabbit Anti-Human POLE2 (a.a. 101-200) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat; Cow; Horse; Sheep

Immunogen

KLH conjugated synthetic peptide derived from human DNA Polymerase epsilon p59: 101-200/527

Conjugate

Application Notes

IHC-P: 1:100-500
IHC-F: 1:100-500
IF: 1:100-500

General Notes

This product (Catalog No. DPABH-13391) is a rabbit-derived IgG polyclonal antibody raised against human POLE2, targeting the amino acid region 101–200 of the protein. This antibody exhibits cross-reactivity with POLE2 from mouse, rat, cow, horse, and sheep. It has been affinity purified by Protein A. DNA polymerase epsilon, which is involved in DNA repair and replication, is composed of a large catalytic subunit and a small accessory subunit. The protein encoded by this gene represents the small subunit (B). Defects in this gene have been linked to colorectal cancer and to combined immunodeficiency.
DPABH-13391 is suitable for use in IHC-P (1:100–1:500), IHC-F (1:100–1:500), IF (immunofluorescence) (1:100–1:500) applications.
DPABH-13391 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

DNA polymerase epsilon subunit 2; DNA polymerase epsilon subunit B; DNA polymerase II subunit 2; DPE 2; DPE2; DPOE2_HUMAN; POLE 2; POLE2; Polymerase (DNA directed) epsilon 2 (p59 subunit); Polymerase (DNA directed) epsilon 2; polymerase (DNA directed), epsilon 2, accessory subunit; Polymerase, DNA, epsilon-2

Entrez Gene ID

UniProt ID