POLE2 (NP_002683, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. The sequence is MAPERLRSRALSAFKLRGLLLRGEAIKYLTEALQSISELELEDKLEKIINAVEKQPLSSN MIERSVVEAAVQECSQSVDETIEHVFNIIGAFDIPRFVYN
Conjugate
Unconjugated
Target
Alternative Names
POLE2; polymerase (DNA directed), epsilon 2, accessory subunit; DPE2; DNA polymerase epsilon subunit 2; DNA polymerase II subunit 2; DNA polymerase epsilon subunit B; polymerase (DNA directed), epsilon 2 (p59 subunit);
POLE2 (polymerase (DNA directed), epsilon 2, accessory subunit) is a protein-coding gene. Diseases associated with POLE2 include colorectal cancer, and among its related super-pathways are Telomere C-strand (Lagging Strand) Synthesis and Mitotic G1-G1/S phases. GO annotations related to this gene include DNA binding and DNA-directed DNA polymerase activity.
Pathway
Activation of the pre-replicative complex; Base excision repair; Cell Cycle, Mitotic; DNA Repair
Citations
Publication ()
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