Anti-TBCE monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human TBCE is used for rabbit immunization.

Conjugate

Alternative Names

TBCE; tubulin folding cofactor E; KCS, Kenny Caffey syndrome , tubulin specific chaperone e; tubulin-specific chaperone E; HRD; KCS1; pac2; Kenny-Caffey syndrome; tubulin-folding cofactor E; KCS;

Entrez Gene ID

UniProt ID

Antigen Description

Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene.

Pathway

Metabolism of proteins, organism-specific biosystem; Post-chaperonin tubulin folding pathway, organism-specific biosystem; Protein folding, organism-specific biosystem;