Anti-SOX6 (aa 1-109) polyclonal antibody

Species Reactivity

Human

Immunogen

SOX6 (NP_201583, 1 a.a. ~ 109 a.a) partial recombinant protein with GST tag. The sequence is MSSKQATSPFACAADGEDAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTLV STIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDR

Conjugate

Alternative Names

SOX6; SRY (sex determining region Y)-box 6; SOXD; HSSOX6; transcription factor SOX-6; SRY-box containing gene 6;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]

Pathway

Endochondral Ossification;