Specifications
Immunogen
Recombinant fragment within Human RRM2. The exact sequence is proprietary.Database link: P31350
Applications
Application Notes
WB: 1/1000 - 1/10000; ICC/IF: 1/100 - 1/250; IP: 1/10 - 1/100.
Target
Alternative Names
RRM2; ribonucleotide reductase M2; ribonucleotide reductase M2 polypeptide; ribonucleoside-diphosphate reductase subunit M2; ribonucleotide reductase small chain; ribonucleotide reductase small subunit; R2; RR2; RR2M;
Product Background
Antigen Description
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
Pathway
Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; E2F mediated regulation of DNA replication, organism-specific biosystem; E2F transcription factor network, organism-specific biosystem; Fluoropyrimidine Activity, organism-specific biosystem; G1/S Transition, organism-specific biosystem; G1/S-Specific Transcription, organism-specific biosystem;
Citations
Publication ()
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COA
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