General Notes
This product (Catalog No. DPABH-05245) is a rabbit-derived polyclonal antibody raised against human PAPSS2. This antibody exhibits cross-reactivity with PAPSS2 from mouse. It has been affinity purified by Protein A. Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.
DPABH-05245 is suitable for use in Western blot (WB) (1:1,000–1:5,000), IHC (1:80–1:400) applications.
DPABH-05245 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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