Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Recombinant fragment, corresponding residues of Human Dynein axonemal intermediate chain 1 (O14576).
Applications
Application Notes
WB: 1/1000 - 1/10000.
Target
Alternative Names
DYNC1I1; dynein, cytoplasmic 1, intermediate chain 1; DNCI1, dynein, cytoplasmic, intermediate polypeptide 1; cytoplasmic dynein 1 intermediate chain 1; DNCIC1; DH IC-1; dynein intermediate chain 1, cytosolic; cytoplasmic dynein intermediate chain 1; dyn
Product Background
Antigen Description
Dynein axonemal intermediate chain 1 belongs to the dynein intermediate chain family. It contains seven WD repeats. The intermediate chains seem to help dynein bind to dynactin 150 kDa component. It may play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores. There are three named isoforms.
Pathway
Phagosome, organism-specific biosystem; Phagosome, conserved biosystem; Salmonella infection, organism-specific biosystem; Salmonella infection, conserved biosystem; Vasopressin-regulated water reabsorption, organism-specific biosystem; Vasopressin-regulated water reabsorption, conserved biosystem;
Citations
Publication ()
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