Suitable for PK bridging ELISA. We recommend the following for sandwich ELISA (Capture - Detection): CABT-ZB1177 - CABT-ZB1179 Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
General Notes
We recommend the following antibody pair to develop a pharmacokinetic (PK) bridging assay to measure free drug: CABT-ZB1177 - CABT-ZB1178 CABT-ZB1179 is recommended for use as a detection antibody when paired with CABT-ZB1177. Vedolizumab (Entyvio) is a humanized IgG1 monoclonal antibody. It is approved for the treatment of ulcerative colitis and Crohn's disease. The drug specifically targets the alpha-4 beta-7 integrin on lymphocytes, blocking their movement into the gastrointestinal tract and thereby reducing gut inflammation.
Target
Alternative Names
Vedolizumab; Entyvio
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
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