Pseudomonas exotoxin A is secreted by Pseudomonas aeruginosa

Product Overview

Pseudomonas exotoxin A is secreted by Pseudomonas aeruginosa

Nature

Native

Tag/Conjugate

Unconjugated

Molecular Weight

66 kDa

Purity

> 95%, by SDS-CGE under reducing conditions

Format

Lyophilized

Buffer

Lyophilized from Tris-HCl buffer

Preservative

None

Storage

2-8°C short term, -20°C long term

Introduction

Pseudomonas aeruginosa is a common bacterium that can cause disease in animals, including humans. It is found in soil, water, skin flora, and most man-made environments throughout the world. It thrives not only in normal atmospheres, but also in hypoxic atmospheres, and has, thus, colonized many natural and artificial environments. It uses a wide range of organic material for food; in animals, the versatility enables the organism to infect damaged tissues or those with reduced immunity. The symptoms of such infections are generalized inflammation and sepsis. If such colonizations occur in critical body organs, such as the lungs, the urinary tract, and kidneys, the results can be fatal. Because it thrives on most surfaces, this bacterium is also found on and in medical equipment, including catheters, causing cross-infections in hospitals and clinics. It is implicated in hot-tub rash. It is also able to decompose hydrocarbons and has been used to break down tarballs and oil from oil spills.

Keywords

Pseudomonas aeruginosa; P. aeruginosa; Pseudomonas; Pseudomonadaceae; Pseudomonadales; Pseudomonas exotoxin; exotoxin A; exotoxin; Pseudomonas aeruginosa toxA; P. aeruginosa toxA