Human THSD7A (a.a 48-1606) protein was expressed in HEK293 cells and fused to 10xHis at the C-terminus
Target
THSD7A
Nature
Recombinant
Tag/Conjugate
His
Molecular Weight
176 kDa
Alternative Names
Thrombospondin, type I; Domain containing 7A
Purity
> 95% , as determined by SDS-PAGE
Format
Liquid
Concentration
Batch dependent - please inquire should you have specific requirements.
Buffer
PBS with 20% glycerol
Preservative
None
Storage
Store at -20°C to -80°C. Avoid multiple freeze/thaw cycles.
Introduction
The protein encoded by this gene is found almost exclusively in endothelial cells from placenta and umbilical cord. The encoded protein appears to interact with alpha(V)beta(3) integrin and paxillin to inhibit endothelial cell migration and tube formation. This protein may be involved in cytoskeletal organization. Variations in this gene may be associated with low bone mineral density in osteoporosis.
Keywords
THSD7A; Thrombospondin Type-1 Domain-Containing Protein 7A; Primary membranous nephropathy; PMN
Citations
Publication ()
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