Treponema Pallidum IgG/IgM ELISA Kit (DEIASL2020)

Regulatory status: For research use only, not for use in diagnostic procedures.

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Size
96T
Sample
Serum, plasma
Intended Use
The Treponema pallidum ELISA Kit provides materials for measurement of antibodies to Treponema pallidum in serum or plasma.
Storage
When stored at 2 °C to 8 °C unopened reagents will retain reactivity until expiration date. Do not use reagents beyond this date.
Do not freeze.
Opened reagents must be stored at 2 °C to 8 °C. Microtiter wells must be stored at 2 °C to 8 °C. Once the foil bag has been
opened, care should be taken to close it tightly again.
Opened kits retain activity for one month if stored as described above.
General Description
Treponema pallidum is a species of spirochaete bacterium with subspecies that cause treponemal diseases such as syphilis, bejel, pinta and yaws. The treponemes have a cytoplasmic and outer membrane. They are not seen on a Gram stained smear because the organism is too thin to be observed under a light microscope. The recent sequencing of the genomes of several spirochetes permits a thorough analysis of the similarities and differences within this bacterial phylum. Treponema pallidum subsp. pallidum has one of the smallest bacterial genomes at 1.14 million base pairs (Mb), and has limited metabolic capabilities, reflecting its adaptation through genome reduction to the rich environment of mammalian tissue. The shape of Treponema pallidum is flat and wavy, unlike the other spirochetes, which are helical.

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References


Giacani, L; Molini, B; et al. Quantitative analysis of tpr gene expression in Treponema pallidum isolates: Differences among isolates and correlation with T-cell responsiveness in experimental syphilis. INFECTION AND IMMUNITY 75:104-112(2007).
Caudie, C; Garel, F; et al. Significance of laboratory findings in cerebrospinal fluid for the diagnosis and survey of six neurosyphills. ANNALES DE BIOLOGIE CLINIQUE 61:563-569(2003).

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