Human Matriptase ELISA Kit

Name: Human Matriptase ELISA Kit
SKU: DEIABL92
Rating: 5 (1 reviews)

Regulatory status: For research use only, not for use in diagnostic procedures.

COA

SDS

Datasheet

Summary

Sample

plasma, serum

Species Reactivity

Human

Intended Use

The Matriptase (human) ELISA Kit is intended for the quantitative determination of the Cancer Antigen Matriptase concentration in human plasma or serum.

Storage

1. Store the kit at 2 - 8°C.
2. Keep microplate sealed in a dry bag with desiccants.
3. The reagents are stable until expiration of the kit.
4. Do not expose reagents to heat, sun, or strong light.

General Description

The protein encoded by the Matriptase gene is an epithelial- derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion and metastasis.

Citations

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Documents

pdf COA

pdf SDS

pdf Datasheet

QA & Reviews

Customer Reviews

References

The Effect of Welding Parameters on the Tensile-Shear Performance of Dissimilar DP600/St14 Resistance Spot Welds

INTERNATIONAL CONFERENCE ON ADVANCES IN MATERIALS AND PROCESSING TECHNOLOGIES, PTS ONE AND TWO

Authors: Pouranvari, M.; Marashi, S. P. H.; Mousavizadeh, S. M.

Abstract

The aim of this paper is to investigate the correlations between the weld macrostructure, the microstructure, failure mode and the mechanical properties (peak load and energy absorption) of dissimilar low carbon steel/dual phase steel (DP600) resistance spot weld. Three distinct failure modes were observed during tensile-shear test: interfacial, pullout and partial thickness-partial pullout failure mode. Results showed that before expulsion, there was a direct relationship between FZ size and mechanical properties. However, on expulsion, peak load and particularly energy absorption were significantly reduced. The reduction of the failure energy was related to PT-PP failure mode. For similar weld size, peak load and energy absorption of the spot welds in PT-PP failure mode was significantly lower than PF mode.

Experimental and numerical FEM-based determinations of forming limit diagrams of St14 mild steel based on Marciniak-Kuczynski model

JOURNAL OF MECHANICAL ENGINEERING AND SCIENCES

Authors: Mianroodi, M.; Altmeyer, G.; Touchal, S.

Abstract

Forming Limit Diagrams (FLD) are used to design metal sheet processes and to choose appropriate material according to their formability. Development of simple and robust methods to determine the formability domain is then a major industrial issue. Marciniak-Kuczynski (M-K) plastic instability criterion is a classical and common approach used to predict numerical FLD. A convergence of the experimental conditions and theoretical M-K hypotheses is investigated. This analysis leads in the proposition of a simple experimental procedure based on classical instrumented biaxial testing machines to reproduce M-K in-plane loading conditions. Experimental results are compared with numerical simulations based on a finite element method implantation of M-K model. This versatile implementation allows the coupling of the plastic instability criterion in ABAQUS with a large range of material behaviors. Application of these experimental and numerical procedures on commercial St14 mild steel leads to the relative differences between lower experimental points and numerical forming limits predictions that do not exceed 4% and 10% in the case of uniaxial and equibiaxial tension for initial prescribed defect ratio of 0.99 and 0.95, and 22% in the case of plane tension. These procedures constitute ways easily implementable in the industry to obtain FLD at reduced costs that show good correlations between experimental results and numerical M-K predictions.