The single B cell antibody approaches harbor the potential to isolate functional mAbs reactive against conformational determinants that are present predominantly in vivo and difficult to emulate in vitro. We provide single B cell antibody service, involving single B cell isolation, sequencing, cloning and screening of single B cell antibodies.
Service Features
Professional project design-Tailoring the immunization, sorting and screening strategy for each project
Species available in our single B cell-based antibody discovery services-human, monkey, rabbit, mouse and rat
Unique immunization-Expertise in DNA, VLP , stable cell line and cell membrane extract immunization
Ex vivo culture of B cells-Cultured supernatant for high throughput FACS, WB or reporter cell assay etc. to help quickly narrow down positive candidates
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