SARS-CoV-2 Nucleoprotein ELISA Kit (DEIASL017)

Regulatory status: For research use only, not for use in diagnostic procedures.

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Size
96T
Sample
Serum, plasma, whole blood
Intended Use
The kit has been verified by high purity SARS-CoV-2 (2019-nCoV) Nucleoprotein/NP Protein. It can recognize recombinant SARS-CoV Nucleoprotein/NP Protein (His Tag), but no react with recombinant MERS-CoV Nucleoprotein/NP protein (His Tag).
Storage
Store at 2 - 8°C and the kit is stable for 6 months upon receipt.
General Description
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

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