Specifications
Applications
Application Notes
Suitable for ADA bridging ELISA.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
General Notes
This antibody is specific for Rituximab. No cross reactivity with other humanized antibodies. It can be used in bridging ELISA for Anti-Drug Antibody (ADA) assay development.
Rituximab (Rituxan) is a chimeric IgG1 monoclonal antibody. It is approved for treating conditions such as non-Hodgkin's lymphoma and rheumatoid arthritis. The drug targets the CD20 antigen on B cells, leading to their destruction and reducing abnormal B cell activity.
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Pallasch, CP; Hallek, M; et al. Incorporating Targeted Agents Into Future Therapy of Chronic Lymphocytic Leukemia. SEMINARS IN HEMATOLOGY 51:235-248(2014).
Lee, SD; Kim, SH; et al. ABO-incompatible living donor liver transplantation without graft local infusion and splenectomy. HPB 16:807-813(2014).