This hybridoma monoclonal antibody is specific for Rituximab.
No cross reactivity with other humanized antibodies.
Suitable for Anti-Drug Antibody (ADA) bridging ELISA assay development.
Summary
Specifications
Antibody Isotype
IgG1
Clone
BZ47
Immunogen
Rituximab
Conjugate
Unconjugated
Applications
Application Notes
Suitable for ADA bridging ELISA. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
General Notes
This antibody is specific for Rituximab. No cross reactivity with other humanized antibodies. It can be used in bridging ELISA for Anti-Drug Antibody (ADA) assay development. Rituximab (Rituxan) is a chimeric IgG1 monoclonal antibody. It is approved for treating conditions such as non-Hodgkin's lymphoma and rheumatoid arthritis. The drug targets the CD20 antigen on B cells, leading to their destruction and reducing abnormal B cell activity.
Citations
Publication ()
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