Product Overview
This item requires custom production and lead time is between 4-12 weeks. We can custom produce based on your specifications.
Purity
> 85% as determined by SDS-PAGE
Format
Liquid or Lyophilized powder
Storage
Store at -20°C/-80°C upon receipt. Avoid repeated freeze-thaw cycles.
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Introduction
Smallpox was an infectious disease unique to humans, caused by either of two virus variants, Variola major and Variola minor. The disease is also known by the Latin names Variola or Variola vera, which is a derivative of the Latin varius, meaning "spotted", or varus, meaning "pimple". The term "smallpox" was first used in Britain in the 15th century to distinguish variola from the "great pox" (syphilis). The last naturally occurring case of smallpox (Variola minor) was diagnosed on 26 October 1977.
Function
Negatively regulates superinfection and syncytium formation in infected host cells. Acts in concert with OPG185/A56 protein at the host cell membrane by interacting with and inhibiting the mature virion entry/fusion complex (EFC). This mechanism ensures that new virions released from the cell cannot enter already infected cells.
Keywords
Vaccinia Virus Superinfection exclusion protein; Protein K2; Serine proteinase inhibitor 3; OPG040; K2L; SPI-3; VACWR033; VACV
Citations
Publication ()
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COA
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