T. pallidum p17 (Partial) [His]

Product Overview

Recombinant T. pallidum p17 protein fused at N-terminus with 6xHis tag was expressed in E. coli and purified by proprietary chromatographic technique.

Nature

Recombinant

Tag/Conjugate

His

Purity

> 95% pure as determined by 10% PAGE (coomassie staining).

Buffer

70mM Tris-HCl pH8.0, 50mM NaCl, 50% Glycerol, 1.5M Urea.

Preservative

None

Storage

2-8°C short term, -20°C long term

Introduction

Treponema pallidum is the causative agent of syphilis. It is a gram negative spirochete, a helical to sinusoidal bacterium with outer and cytoplasmic membranes, a thin peptidoglycan layer, and periplasmic flagella.

Antigen Description

p17 is a 17-kDa major membrane lipoprotein of Treponema pallidum. Primary syphilis is characterized by the prevalence of IgG to protein p41 with the total antibody level being low, while early latent syphilis is characterized mainly by prevalence of IgG to protein p17 in the presence of high titers of antibodies.

Keywords

T. pallidum; Treponema pallidum; T. Pallidum p17; Treponema Pallidum p17