Product Overview
A DNA sequence encoding the complete ORF of the S100A7 gene (a.a 1-101) was expressed with a GST-tag at N-terminal
Alternative Names
S100A7; SA7-100; SA7-100 protein
Concentration
Batch dependent - please inquire should you have specific requirements
Buffer
50 mM Tris-HCI, 10 mM reduced glutathione, pH=8.0 in the elution buffer
Storage
Store at -80 °C. Avoid repeated freeze/thaw cycles
Introduction
S100A7, also known as Psoriasin, belongs to the S-100 family of calcium binding proteins and is secreted via a non-classical secretory pathway into the cytoplasm. It is thought to function in the regulation of many cellular processes, including the cell cycle, cell progression and cellular differentiation. It contains two EF-hand domains and is highly upregulated in psoriatic epidermis, as well as in bladder squamous cell carcinoma and breast cancer tissue, suggesting a possible role in carcinogenesis. Recombinant human S100A7 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Keywords
S100A7; Psoriasin; S-100
Citations
Publication ()
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