Powassan virus (POWV) is a positive-sense single-stranded RNA virus that belongs to the genus Flavivirus, a member of the Flaviviridae family of viruses. It is an arthropod-borne virus that is transmitted by infected ticks to small/medium sized mammals, which act as reservoirs for the virus. Different tick species transmit POWV including hard ticks, of the family Ixodidae, and the tick species varies according to the geographical region. POWV can also be transmitted to humans, which are incidental, dead-end, hosts for the virus. POWV NS1 protein 1 (Non-Structural protein 1) has been manufactured in response to the unmet need for highly purified, concentrated protein for use in serological based diagnostic assays.
Keywords
Powassan virus; POWV; pre-membrane
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