Full-length cDNA coding for human DFS70 protein fused to a decahistidine purification tag. Expressed by recombinant baculovirus infection of Spodoptera Sf9 insect cells.
Target
DFS70
Nature
Recombinant
Tag/Conjugate
His
Molecular Weight
62 kDa
Alternative Names
DFS70; Dense Fine Speckles 70 kDa; PSIP2; LEDGF; p75
Purity
> 80%
Format
Liquid
Buffer
Neutral to slightly alkaline pH and 20% glycerol as cryoprotective agent.
Preservative
None
Storage
Store at -70°C or below. Repeated freeze/thaw cycles should avoided.
Introduction
DFS70 is identical with lens epithelium-derived growth factor/transcription coactivator p75 (LEDGF/p75), a transcription factor attached to chromatin throughout the cell cycle. LEDGF/p75 has been reported to be involved in the cellular stress response as well as the integration of lentiviruses into host chromosomes.
Keywords
DFS70; Dense Fine Speckled; DFS; LEDGF/p75; PSIP1
Citations
Publication ()
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