Recombinant DENV 2 envelope Protein [His] (DAG-T2710)

Recombinant Dengue virus 2 envelope Protein from E. coli [His]

Nature
Recombinant
Tag/Conjugate
His
Molecular Weight
13.8 kDa
Alternative Names
DENV envelope
Purity
> 95% pure
Format
Liquid
Concentration
500 ug/ml
Size
100 ug
Buffer
Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Preservative
None
Storage
Can be stored at 4 ℃ short term. For long term storage, aliquot and store at -20 °C or -70 °C. Avoid repeated freezing and thawing cycles.
Introduction
Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. This protein is synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes.
Keywords
Dengue virus; DENV; DENV envelope

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