Tag/Conjugate
Unconjugated
Alternative Names
Adeno-associated Virus; AAV; AAV5
Purity
> 95 % as determined by SDS-PAGE
Concentration
1.6x10^12 VPs
Storage
Store at -80°C for long term
Introduction
Adeno-Associated Virus (AAV) is a nonpathogenic virus species that belongs to the Parvoviridae family. AAV is classified as small (25nm) and contains a single-stranded nonenveloped DNA genome. Infection with AAV occurs only with the help of other viruses, either herpesvirus or adenovirus (hence adeno-associated virus), causing only a very mild immune response in humans. There are twelve serotypes of human AAV but the number of nonhuman AAVs exceeds 100.
Keywords
Adeno-Associated Virus ; AAV; AAV5
Citations
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Castle, MJ; Gershenson, ZT; et al. Adeno-Associated Virus Serotypes 1, 8, and 9 Share Conserved Mechanisms for Anterograde and Retrograde Axonal Transport. HUMAN GENE THERAPY 25:705-720(2014).
Hu, CH; Kasten, J; et al. Myocyte-mediated Arginase Expression Controls Hyperargininemia but not Hyperammonemia in Arginase-deficient Mice. MOLECULAR THERAPY 22:1792-1802(2014).