Tag/Conjugate
Unconjugated
Alternative Names
Adeno-associated Virus; AAV; AAV2
Purity
> 95 % as determined by SDS-PAGE
Concentration
1.6x10^12 VPs
Storage
Store at -80°C for long term
Introduction
Adeno-Associated Virus (AAV) is a nonpathogenic virus species that belongs to the Parvoviridae family. AAV is classified as small (25nm) and contains a single-stranded nonenveloped DNA genome. Infection with AAV occurs only with the help of other viruses, either herpesvirus or adenovirus (hence adeno-associated virus), causing only a very mild immune response in humans. There are twelve serotypes of human AAV but the number of nonhuman AAVs exceeds 100.
Keywords
Adeno-Associated Virus ; AAV; AAV2
Citations
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Q & A
Q: Is this product recombinant protein? If yes, please let us know the expression systems of this product?
A: Cat#DAG-WT824 are well-characterized recombinant AAV capsids devoid of any viral genomic material that are widely used as reference materials during the development of AAV-based gene therapies.
The expression system for this product is HEK293T cells.
Q: Could you please tell us the information of preservatives?
A: Our AAV virus-like particles are stored in a PBS-based buffer and are shipped on dry ice.
Customer Reviews
Yuan, HJ; Guy, J; et al. Mutant HumanT8993G ATP6 Expression by a Mitochondrial Targeting Sequence Modification of AAV Capsid VP2 in Transgenic Mice. MOLECULAR THERAPY 22:S235-S235(2014).
Collaud, F; Ronzitti, G; et al. An Optimized AAV Vector for Liver-Directed Expression of the UGT1A1 Gene in Crigler-Najjar Syndrome, towards Clinical Development. MOLECULAR THERAPY 22:S110-S110(2014).
COA
Certificate of Analysis
