Tag/Conjugate
Unconjugated
Alternative Names
Adeno-associated Virus; AAV; AAV1
Purity
> 95 % as determined by SDS-PAGE
Concentration
1.6x10^12 VPs
Storage
Store at -80°C for long term
Introduction
Adeno-Associated Virus (AAV) is a nonpathogenic virus species that belongs to the Parvoviridae family. AAV is classified as small (25nm) and contains a single-stranded nonenveloped DNA genome. Infection with AAV occurs only with the help of other viruses, either herpesvirus or adenovirus (hence adeno-associated virus), causing only a very mild immune response in humans. There are twelve serotypes of human AAV but the number of nonhuman AAVs exceeds 100.
Keywords
Adeno-Associated Virus ; AAV; AAV1
Citations
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Wu, HY; O'Neill, B; et al. Restoration of cocaine stimulation and reward by reintroducing wild type dopamine transporter in adult knock-in mice with a cocaine-insensitive dopamine transporter. NEUROPHARMACOLOGY 86:31-37(2014).
Schmidt, C; Bezuidenhout, D; et al. A slow-release fibrin matrix increases adeno-associated virus transduction of wound repair cells invivo. JOURNAL OF BIOMATERIALS APPLICATIONS 28:1408-1418(2014).