Rat beta Amyloid (1-42) Peptide

Product Overview

Rat β-Amyloid (1-42) is a 42-amino-acid fragment derived from the amyloid precursor protein (APP). It readily self-aggregates into oligomers and fibrils, with the oligomeric form being the most neurotoxic. These aggregates contribute to amyloid plaque formation—a hallmark of Alzheimer's disease—disrupting cellular function, impairing mitochondrial activity, and promoting neuronal cell death via oxidative stress, calcium dysregulation, and inflammatory pathways.

Nature

Synthetic

Molecular Weight

4418.02 g/mol

Purity

>95%

Format

Lyophilized

Preservative

None

Storage

Store at -20°C

Reconstitution

Aqueous solution of ammonium hydroxide at a 1% (w/v)

Keywords

Amyloid beta 42-1; Aβ42