Anti-LDHB monoclonal antibody, clone 3I7

Antibody Isotype

IgG1

Clone

3I7

Species Reactivity

Human

Immunogen

LDHB (AAH02362, 1 a.a. ~ 335 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Alternative Names

lactate dehydrogenase B; EC 1.1.1.27; Renal carcinoma antigen NY-REN-46; OTTHUMP00000165231; LDH-B; TRG-5; LDH-H; L-lactate dehydrogenase B chain; LDH heart subunit; EC 1.1.1; OTTHUMP00000165228; OTTHUMP00000165229

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on the X chromosome and on chromosome. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Mouse monoclonal antibody raised against a full length recombinant LDHB.

Pathway

Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Glycolysis / Gluconeogenesis, organism-specific biosystem; Glycolysis / Gluconeogenesis, conserved biosystem; Glycolysis and Gluconeogenesis, organism-specific biosystem; Metabolic pathways, organism-specific biosystem.