The Benzo(a)Pyrene ELISA is an immunoassay for the quantitative and sensitive detection of Benzo(a)Pyrene in water samples.
Storage
The Benzo(a)Pyrene ELISA should be stored in the refrigerator (4–8°C).
Detection Limit
0.30 ppb (ug/L).
General Description
Benzo(a)Pyrene (B(a)P) is an environmental pollutant emanating from both natural and anthropogenic sources. B(a)P is produced during incomplete combustion, pyrolysis of organic matter, during industrial processes and during household activities such as cooking, barbequing and smoking. Anthropogenic sources such as industrial production, transportation and waste incineration generate significant amount of this compound and other PAHs. Petroleum production, import and export of petroleum products also contribute to the contamination of marine samples. Other sources include crude oil contamination of ground and sea water (such as in oil spills), tobacco smoke, exhaust fumes and combustion of all forms of fossil fuels. Benzo(a)Pyrene being fat soluble tends to accumulate in marine organisms and contaminated coastal environments. B(a)P is a carcinogen known to induce tumors in a number of organs in animal models and humans. One of its metabolites is known to form DNA adducts which are responsible for mutagenesis and tumorigenesis. Due to the carcinogenic and mutagenic nature of PAHs, there has been increased concern in their detection and monitoring in recent years. Regulatory levels have been set for B(a)P in various countries.
Citations
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