General Notes
This product (Catalog No. DPATB-H82281) is a rabbit-derived polyclonal antibody raised against human TRPV1. This antibody exhibits cross-reactivity with TRPV1 from mouse and rat. It has been affinity purified by Protein A. Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.
DPATB-H82281 is suitable for use in WB 1 (500-1:2000), IF/ICC 1 (100-1:500) applications.
DPATB-H82281 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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