Specifications
Immunogen
Protein expressed in 293T cell transfected with human IDH1 expression vector
Applications
Application Notes
WB: 1:2000; IHC: 1:50; IF: 1:100;
Target
Alternative Names
IDH1; isocitrate dehydrogenase 1 (NADP+), soluble; isocitrate dehydrogenase [NADP] cytoplasmic; NADP(+)-specific ICDH; oxalosuccinate decarboxylase; NADP-dependent isocitrate dehydrogenase, cytosolic; NADP-dependent isocitrate dehydrogenase, peroxisomal;
Product Background
Antigen Description
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.
Pathway
Citrate cycle (TCA cycle), organism-specific biosystem; Citrate cycle (TCA cycle), conserved biosystem; Citrate cycle, first carbon oxidation, oxaloacetate =>2-oxoglutarate, organism-specific biosystem; Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate, conserved biosystem; Glutathione metabolism, organism-specific biosystem;
Citations
Publication ()
Have you cited CAB-9292MH in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
