HIV type 1 Pol Integrase protein [His] (DAG3537)

HIV type 1 Pol Integrase protein [His], recombinant protein from E. coli Datasheet

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Product Overview
Recombinant Human immunodeficiency virus-I pol Integrase, His-tagged
Specificity
Immunoreactive with all sera of HIV-1 infected individuals.
Nature
Recombinant
Tag/Conjugate
His
Purity
Greater than 95.0% as determined by HPLC analysis and SDS-PAGE.
Preservative
Sterile filtered colorless clear solution. 1.5 M urea + 25 mM Tris-HCl, pH 8.0 + 0.2% Triton-X and 50% Glycerol.
Storage
2-8°C short term, -20°C long term
Introduction
HIV-1 is the most common and pathogenic strain of the virus. Scientists divide HIV-1 into a major group (Group M) and two or more minor groups. Each group is believed to represent an independent transmission of SIV into humans (but subtypes within a group are not). A total of 39 ORFs are found in all six possible reading frames (RFs) of HIV-1 complete genome sequence, but only few of them are functional.
Antigen Description
Integrase is an enzyme produced by the HIV which enables its genetic material to be integrated into the DNA of the infected cell and is a key component in the pre-integration complex. HIV integrase contains 3 domains, an N-terminal HH-CC zinc finger domai
Keywords
HIV 1; HTLV3; Human Immunodeficiency Virus 1

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