Product Overview
Human PLA2R1 (a.a 21-1397) protein was expressed in HEK293 cells and fused to 10xHis at the C-terminus
Molecular Weight
160.7 kDa
Alternative Names
phospholipase A2 receptor 1; PLA2R1
Purity
> 95% , as determined by SDS-PAGE
Format
Liquid or Lyophilized powder
Concentration
Batch dependent - please inquire should you have specific requirements.
Buffer
Lyophilized from sterile PBS, pH 7.4, with 5% Trehalose
Storage
Store at -20°C to -80°C for up to 12 months in lyophilized form. After reconstitution, if not used within one month, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles.
Introduction
This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.
Keywords
PLA2R1; PLA2R; M-type phospholipase A2 receptor; Primary membranous nephropathy; PMN
Citations
Publication ()
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COA
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