Medica 2026
Nov 16-19, 2026 - Düsseldorf, Germany

Hapten Conjugates with Matching Antibodies for Sex Hormone Testing

The three main classes of sex hormones are androgens, estrogens and progestogens, which play important roles in various physiological processes. In general, androgens are considered "male sex hormones", while estrogens and progestogens are considered "female sex hormones". Creative Diagnostics offers a comprehensive range of high quality hapten conjugates with matching antibodies validated for the in vitro quantitative measurement of sex hormone concentrations in water or biological fluid samples.

Product Highlights

  • Offers a wide variety of conjugate options
  • Suitable for use in ELISA, LF, CLIA, etc
  • Robust performance in a wide range of samples
  • Antigens and antibodies are available in bulk volumes

Steps in steroid hormone biosynthesis Fig. 1 Steps in steroid hormone biosynthesis (Olson SH, et al. 2007)

Androgens

Androgens are an important class of steroid hormones that control normal male development and reproductive function. They have characteristic roles during male sexual differentiation, but also during development and maintenance of secondary male characteristics and during initiation and maintenance of spermatogenesis. Testosterone together with its potent metabolite, dihydrotestosterone (DHT), are the principal androgens in the circulation of mature male mammals.

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Estrogens

Estrogens are an important class of steroid hormones that control the development of female secondary sexual characteristics. In premenopausal women, estrogens are produced primarily in the ovaries, corpus luteum, and placenta. The three majors naturally occurring estrogens in women are estrone (E1), estradiol (E2), and estriol (E3). E2 is the major product from the whole biosynthesis process and is the most potent estrogen during the premenopausal period in a woman's life. E1 plays a larger role after menopause. During pregnancy E3 is the predominant circulating estrogen in terms of serum levels. Though E3 is the most plentiful of the three estrogens it is also the weakest.

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Progestogens

Progesterone, the most important and only naturally occurring human progestogen, is produced primarily in the ovaries. The hormone helps regulate menstruation, prepares the body for pregnancy, and aids in nourishing the uterine environment to support implantation of the fertilized egg, as well as growth of the placenta. Normal progesterone levels are also important for a normal body composition. Progesterone levels may be monitored through simple blood serum testing if necessary.

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References

  1. Handelsman DJ. (2020). Androgen Physiology, Pharmacology, Use and Misuse. Endotext.
  2. McEwan IJ, Brinkmann AO. (2021). Androgen Physiology: Receptor and Metabolic Disorders. Endotext.
  3. Cui J, Shen Y, Li R. (2013). Estrogen synthesis and signaling pathways during aging: from periphery to brain. Trends in molecular medicine. 19(3), 197–209.
  4. Olson SH, Bandera EV, Orlow I. (2007). Variants in Estrogen Biosynthesis Genes, Sex Steroid Hormone Levels, and Endometrial Cancer: A HuGE Review, American Journal of Epidemiology. 165(3), 235–245.
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Product List

Cat_NProduct Name
DAGPY6646Dehydroepiandrosterone [BSA]Inquiry    
DCABY-010Anti-Dehydroepiandrosterone monoclonal antibody, clone 2-8.2 (CHO/2288/282)Inquiry    
DCABY-011Anti-Dehydroepiandrosterone monoclonal antibody, clone 2-23.3 (CHO/2288/2233)Inquiry    
DCABY-017Anti-Dehydroepiandrosterone monoclonal antibody, clone 2-35.2 (CHO/2288/2352)Inquiry    
DAG1309Testosterone-3 [HRP]Inquiry    
DAGF-024Testosterone-3 [BSA]Inquiry    
CABT-B9035Anti-Testosterone monoclonal antibody, clone IN634Inquiry    
DAGB348Estrone [HRP]Inquiry    
DAGA-148BEstrone [BSA]Inquiry    
CABT-L2616Mouse Anti-Estrone 3 glucuronide monoclonal antibody, clone IN768Inquiry    
DAGA-025B-HRPEstradiol [HRP]Inquiry    
DAGA-025BEstradiol [BSA]Inquiry    
HMABPY028RHA™ anti-Estradiol monoclonal antibody, clone E2Inquiry    
DAG1185Estriol-6 [HRP]Inquiry    
DAG2988Estriol-6 [BSA]Inquiry    
DCABY-4412Magic™ Anti-Estriol monoclonal antibody, clone N2320FTUInquiry    
DCABY-4413Magic™ Anti-Estriol monoclonal antibody, clone N2300FTU3Inquiry    
DAG3019Progesterone-11 [BSA]Inquiry    
DAG3019HProgesterone-11 [HRP]Inquiry    
HMABPY023RHA™ anti-Progesterone monoclonal antibody, clone pInquiry    
DAG99917-Hydroxypregnenolone [HRP]Inquiry    
DAGA-156B17-Hydroxypregnenolone [BSA]Inquiry    
DMABT-Z60396Anti-Hydroxyprogesterone monoclonal antibody, clone JRUQ-3Inquiry    
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