Medica 2026
Nov 16-19, 2026 - Düsseldorf, Germany

cTnI Antibody Pairs for Sandwich Immunoassays

Creative Diagnostics is constantly working in order to bring best-in–market reagents for troponin measurements. Now we are offering new reagents for Troponin-I antibody pair for the development of highly sensitive and specific cTnI sandwich immunoassays.

All of the anti-troponin I monoclonal antibodies have been on the clinical diagnostic market since 1998. Among them, clone TPC110 have dominated about 70% of US clinical diagnostic market since 1998. It is still one of the most popular monoclonal antibodies (N24-40 position) for the imunodiagnostic applications of Myocardial Infarction.

Need antibodies in bulk quantities or custom packaging?
Inquire now. Complete Request Form

The cardiac marker Troponin I (cTnI) is useful for the diagnosis of myocardial infarction (MI) and the risk stratification to help guide the choice of therapeutic options. The cardiac-specific troponins, Troponin-I (cTnI) and Troponin-T (cTnT) are considered the biochemical markers of choice in the evaluation of acute coronary syndromes (ACS). Elevated levels of cTnI in patients have a statistically significant increase in mortality or increases in other non-fatal cardiac events such as non-fatal MI, congestive heart failure, and urgent revascularization.

Table 1: List of Anti-Troponin I Monoclonal Antibodies

AntibodiesKdEpitope location
DMAB4456MH0.46nMN 24-40Inquiry    
DMAB4452MH0.37nMN 24-40Inquiry    
DCAB-TJ2020.76nMN 24-40Inquiry    
DCAB-TJ2010.39nMN 59-79Inquiry    
DCAB-TJ2031.93nMN 80-95Inquiry    

Table 2: Pairing Schemes for Sandwich Enzyme Immunoassays

CaptureDetection (HRP conjugated)Min. Sensitivity (ng/ml)
DCAB-TJ202DMAB4456MH/DMAB4452MH0.2
DCAB-TJ201DMAB4456MH/DMAB4452MH0.1 *
DCAB-TJ203DMAB4456MH/DMAB4452MH0.3
DCAB-TJ202 and DCAB-TJ201 (1:1)DMAB4456MH/DMAB4452MH0.1
DCAB-TJ202 and DCAB-TJ201 and DCAB-TJ203 (1:1:1)DMAB4456MH/DMAB4452MH0.1

*Rated as one of the best pairing for ELISA of troponin I.

Inquiry Basket
loading Loading ......

Inquiry

Inquiry