COVID-19 Antigen Lateral Flow Assay Development

In response to the COVID-19 pandemic, Creative Diagnostics is now offering the SARS-CoV-2 nucleoprotein antibody pair for rapid COVID-19 antigen assays to equip healthcare workers for rapid COVID-19 antigen detection. We also offer SARS-CoV-2 antigen extraction buffer tubes that can be used as packing supplies for SARS-CoV-2 antigen extraction.

SARS-CoV-2 Nucleoprotein Antibody Pair for Rapid COVID-19 Antigen Assays

The global COVID-19 pandemic has created an urgent demand for accurate rapid point of care testing. Antigen-based assays are suitably inexpensive and can be rapidly mass-produced, but sufficiently accurate performance requires highly optimized antibodies and assay conditions. Creative Diagnostics team has tested hundreds of anti-nucleocapsid antibody pairs to recommend you the best pair for further development of an LFA for SARS-CoV-2 Antigen.

SARS-CoV-2 MAb Pairs with Proven Performance in Commercially Launched Rapid Antigen COVID-19 Assays

Cat. No.	Product Name	Source	Application
CABT-MMB1	Mouse Anti-SARS-CoV-2 NP monoclonal antibody, clone NB1	Mouse	Capture
CABT-MMB2	Mouse Anti-SARS-CoV-2 NP monoclonal antibody, clone NB2	Mouse	Detection
CABT-RMJ1	Rabbit anti-SARS-CoV-2 NP monoclonal antibody, clone NJ1	Rabbit	Detection

Best pairs in lateral flow： If you are developing a lateral flow -based test, we recommend you start with these two capture-detection pairs: CABT-MMB1-CABT-MMB2, CABT-MMB1-CABT-RMJ1.

We have validated that our key anti-NP clones NB1, NB2, and NJ1 are able to detect the UK variant. The South African variant of SARS-CoV-2 (known as 501.V2, 20C/501Y.V2 or B.1.351 lineage) does not have any mutations in its nucleoprotein and should be detected by all our anti-COVID-19 NP MAbs.

Product Information

Antibody are validated for rapid antigen assays and in commercially launched assays around the world
The confirmed LOD for direct swab was 1.5 x 102 TCID50/mL
Can also detect D614G strain, no cross reactivity to other coronaviruses
Used in assays where specimen is nasopharyngeal or saliva
Manufactured in large sale from mg to g

SARS-CoV-2 Antigen Extraction Buffer Tubes

Extraction Buffer Tubes Brochure

These plastic tubes are designed to extract SARS-CoV-2 antigen from nasopharyngeal swab, which can be used as packing supplies for SARS-CoV-2 Rapid Antigen Test development and production.

PRODUCT HIGHLIGHTS

Soft plastic that allows easy squeeze on the tube sides to fully extract the liquid from the swab
Slim tube design reduces the need for the amount of extraction buffer, thereby increasing the concentration of the virus antigen in the sample and improving the positive detection rate of virus antigen
Integral dispensing tip design
Provide customizing and OEM services

PRODUCT	CAT. NO.	PACKING	PRICE
Extraction Tube 1	TUBE-CD01	5000	Inquiry
Extraction Tube 3	TUBE-CD03	5000	Inquiry
Extraction Tube 4	TUBE-CD04	5000	Inquiry
Extraction Tube 7	TUBE-CD07	5000	Inquiry
Extraction Tube 8	TUBE-CD08	5000	Inquiry

SARS-CoV-2 Antigen Extraction Buffer

The lysis buffer is used for rapid extraction of virus antigen from virus cultures and throat swab samples. This product can improve virus lysis efficiency and the accuracy of antigen detection. It is suitable for various diagnostic technology platform, such as colloidal gold immunoassay, immunofluorescence chromatography and chemiluminescence. This product is provided in liquid form with pH 7.4, which contains Tween-20, ProClin-300 etc.

PRODUCT NAME	CAT. NO.	PACKING	PRICE
SARS-CoV-2 Antigen Extraction Buffer	CD-AEB01	100 mL, 1 L	Inquiry

We remain focused on our mission to serve life scientists to achieve their mission, faster. We know that many scientists are still diligently pursuing their research, particularly those focused on COVID-19. We continue to support our customers and partners worldwide.