Creative Diagnostics offers a large range of Chikungunya antigens and antibodies. These antibodies and antigens have been validated to work in various types of immunoassays and can be supplied as high quality research tools to develop sensitive and specific infectious disease assays.
Antigens to Chikungunya Virus
|Cat. No.||Product Name||Expression System||Nature|
|DAG3056||CHIKV E1 protein (aa 1 - 415)||Baculovirus||Recombinant|
|DAGA-161||Chikungunya E1 Antigen (E.coli)||E.coli||Recombinant|
|DAGA-413||Recombinant Chikungunya Virus Wild gp E1 [His]||Drosophila S2 cells||Recombinant|
|DAGA-414||Recombinant Chikungunya Virus Mutant gp E1 [His]||Drosophila S2 cells||Recombinant|
|DAGA-163||Chikungunya E1 E2 Composite Antigen (E.coli)||E.coli||Recombinant|
|DAGA-292||CHIKV Capsid protein [His]||E.coli||Recombinant|
|DAGA-415||Recombinant Chikungunya Virus wild gp E2 [His]||Sf-9 insect cells||Recombinant|
|DAGA-259||CHIKV Envelope Antigen 2 (aa 339-692) [His6]||E.coli||Recombinant|
Antibodies to Chikungunya Virus
Anti-CHIKV Env monoclonal antibody, clone IN452 (CABT-B8657)
Anti-CHIKV Env monoclonal antibody, clone IN449 (CABT-B8658)
Anti-CHIKV monoclonal antibody, clone N97701 (CABT-B8659)
Anti-CHIKV monoclonal antibody, clone N97702 (CABT-B8660)
Anti-Chikungunya E1 monoclonal antibody (CABT-BL8724)
Anti-CHIKV 181/25 polyclonal antibody (CABT-B1086)
Anti-CHIKV E2 polyclonal antibody (CABT-B1087)
Chikungunya Virus Background:
Chikungunya virus (CHIKV) is an arthropod-borne alphavirus primarily transmitted by Aedes mosquitoes, which has been capable of causing explosive outbreaks of human disease in over 60 countries in Asia, Africa, Europe and the Americas.
CHIKV consists of three structural proteins and four nonstructural proteins. The capsid and two envelope glycoproteins: E1 and E2 are the structural proteins. E1 and E2 proteins both have a molecular weight of roughly 50kDa and form a heterodimer anchored in the membrane. The mature vision contains 240 heterodimer spikes of E2/E1, which after release, bud on the surface of the infected cell, where they are released by exocytosis to infect other cells.
CHIKV is transmitted by the bites of infected female mosquitoes from human to human. The mosquitoes most commonly are Aedes aegypti and Aedes albopictus. Chikungunya virus infection causes an illness with symptoms similar to those of the dengue fever with an abrupt onset of fever frequently accompanied by joint pain. Other common signs and symptoms include muscle pain, headache, nausea, fatigue and rash.