Biological Activity: Measured by the ability of the coated antibody to induce degranulation of activated NK cells and to enhance IFNγ secretion by non-activated NK cells
Summary
Specifications
Antibody Isotype
IgG2a, κ
Clone
M57
Species Reactivity
Human
Immunogen
Recombinant human NKp46/Fc (CD335)
Conjugate
Unconjugated
Applications
Application Notes
Functional assay Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Target
Alternative Names
NCR1; natural cytotoxicity triggering receptor 1; LY94, lymphocyte antigen 94 (mouse) homolog (activating NK receptor; NK p46); CD335; NK p46; NKP46; NK cell-activating receptor; natural killer cell p46-related protein;
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