Native ritirachium album limber Proteinase K

Target

Proteinase K

Nature

Native

Bio-activity

>30 U/mg

Format

Solid

Buffer

50mM Tris-HCl, pH7.5,10mM CaCl2

Preservative

None

Storage

Store at 2 to 8°C

Ship

Wet ice

Introduction

In molecular biology Proteinase K (also protease K or endopeptidase K) EC 3.4.21.64 is a broad-spectrum serine protease. The enzyme was discovered in 1974 in extracts of the fungus Engyodontium album (formerly Tritirachium album). Proteinase K is able to digest native keratin (hair), hence, the name "Proteinase K". The predominant site of cleavage is the peptide bond adjacent to the carboxyl group of aliphatic and aromatic amino acids with blocked alpha amino groups. It is commonly used for its broad specificity. This enzyme belongs to Peptidase family S8. The molecular weight of Proteinase K is 28,900 daltons (28.9 kDa).

Keywords

Ritirachium album limber; Proteinase K