Buffer
PBS, 50% Glycerol, 1.45% Sodium chloride, pH7.4
Introduction
Matrix metallopeptidase 9 (MMP-9), also known as 92 kDa type IV collagenase, 92 kDa gelatinase or gelatinase B (GELB), is a matrixin, a class of enzymes that belong to the zinc-metalloproteinases family involved in the degradation of the extracellular matrix. In humans the MMP9 gene. encodes for a signal peptide, a propeptide, a catalytic domain with inserted three repeats of fibronectin type II domain followed by a C-terminal hemopexin-like domain.
Keywords
MMP9; Matrix metallopeptidase 9
Citations
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Bao, W; Min, D; et al. Monocyte CD147 is induced by advanced glycation end products and high glucose concentration: possible role in diabetic complications. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 299:C1212-C1219(2010).
Xiao, LJ; Lin, P; et al. ADAM17 targets MMP-2 and MMP-9 via EGFR-MEK-ERK pathway activation to promote prostate cancer cell invasion. INTERNATIONAL JOURNAL OF ONCOLOGY 40:1714-1724(2012).