Concentration
Batch dependent - please inquire should you have specific requirements.
Buffer
50 mM Glycine, 140 mM NaCl, 0.1% CHAPS and 0.01% SDS, pH 9.0
Storage
Store at -80°C. Avoid multiple freeze/thaw cycles
Introduction
Feline immunodeficiency virus (FIV) is a lentivirus that affects domesticated housecats worldwide and is the causative agent of feline AIDS. From 2.5% up to 4.4% of cats worldwide are infected with FIV. FIV differs taxonomically from two other feline retroviruses, feline leukemia virus (FeLV) and feline foamy virus (FFV), and is more closely related to human immunodeficiency virus HIV. Within FIV, five subtypes have been identified based on nucleotide sequence differences coding for the viral envelope (env) or polymerase (pol). FIV is the only non-primate lentivirus to cause an AIDS-like syndrome, but FIV is not typically fatal for cats, as they can live relatively healthily as carriers and transmitters of the disease for many years. A vaccine is available although its efficacy remains uncertain, and cats will test positive for FIV antibodies after vaccination.
Keywords
Feline immunodeficiency virus; FIV; Petaluma
Inactivation
Photochemical and detergent treated
Citations
Publication ()
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