Sample
Serum, plasma, tissue homogenates, cell culture supernatants, other biological fluids
Intended Use
This Kit allows for the determination of SeV concentrations in Mouse serum, cellculture supernates and other biological fluids.
Storage
Store kit reagents at 2-8 °C for 6 months. Immediately after use remaining reagents should be returned to cold storage at 4 °C.
Detection Range
1.25 ng/L - 20 ng/L
Detection Limit
The minimum detectable dose (MDD) of Mouse SeV is typically less than 0.1 ng/L.
General Description
Sendai virus (SeV), also known as murine parainfluenza virus type 1 or hemagglutinating virus of Japan (HVJ), Murine respirovirus, is a negative sense, single-stranded RNA virus of the family Paramyxoviridae. The virus was isolated in the city of Sendai in Japan in the early 1950s. Since then, it has been actively used in research as a model pathogen. The virus is responsible for a highly transmissible respiratory tract infection in mice, hamsters, guinea pigs, rats, and occasionally marmosets, with infection passing through both air and direct contact routes. Natural infection occurs by way of the respiratory tract. In animal facility airborne transmission can occur over a distance of 5–6 feet as well as through air handling systems.
Citations
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