Intended Use
This product is used for in vitro quantitative detection of anti-SARS-CoV-2 IgG1 antibodies in mouse serum, plasma and other culture samples. It can help assess the amount of IgG1 antibodies produced by mouse after immunization or mouse IgG1 antibodies expressed in cell culture.
Storage
This test kit must be stored at 2 – 8°C upon receipt. For the expiration date of the kit refer to the label on the kit box. All components are stable until this expiration date.
Precision
Intra-Assay: CV<15%
Inter-Assay: CV<15%
Detection Range
0.046875ng/mL - 3ng/mL
Detection Limit
The minimum detectable concentration of this product for total antibodies is not higher than 30 pg/mL.
Citations
Publication ()
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COVID-19 Infection Enhances Susceptibility to Oxidative Stress-Induced Parkinsonism
Smeyne RJ, Eells JB, Chatterjee D, Byrne M, Akula SM, Sriramula S, O'Rourke DP, Schmidt P
Applications: ELISA
Reactive species: Mouse
"Abstract: Background:Viral induction of neurological syndromes has been a concern since parkinsonian-like features were observed in patients diagnosed with encephalitis lethargica subsequent to the 1918 influenza pandemic. Given the similarities in the systemic responses after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection with those observed after pandemic influenza, there is a question whether a similar syndrome of postencephalic parkinsonism could follow coronavirus disease 2019 infection. Objective:The goal of this study was to determine whether prior infection with SARS-CoV-2 increased sensitivity to a mitochondrial toxin known to induce parkinsonism."
Article snippet: Antibody titers were measured in plasma using the Mouse Anti-SARS-CoV-2 IgG Antibody ELISA Kit (DEIASL240) from CD Creative Diagnostics (NY, NY) according to the manufacturer's instructions. 
Figure 1. Antibody titers in mice infected 45 days before testing.
COA
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