Product Name
Lipopolysaccharides (LPS) (Salmonella typhimurium, vaccine adjuvant)
Subclassification
Vaccine grade-PRR Ligands-based adjuvant
Storage
Shipped at room temperature and it should be stored at 2-8°C. Long term storage at -20°C for up to 2 years. Avoid repeated freeze thaw cycles
Recommended Usage
Cell culture : add 1 ml of sterile balanced salt solution or cell culture medium to a vial (1 mg) and swirl gently until the powder dissolves. Solutions can be further diluted to the desired working concentration with additional sterile balanced salt solutions or cell culture media.
Description
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety
stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs). This product is phenol extracted from Salmonella Typhimurium.
This LPS has been used to induce NOS in rats and guinea pigs. Bacteria with common serotypes have surface antigens (group O, group H, or LPS) which generate the same antibody response.
Format
Provided as a lyophilized powder; sterile. Colorless to Light Yellow liquid
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