Specifications
Immunogen
Synthetic peptide derived from human LINGO4
Applications
Application Notes
Suitable for ICC/IF
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Citations
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Pepinsky, RB; Shao, ZH; et al. Exposure Levels of Anti-LINGO-1 Li81 Antibody in the Central Nervous System and Dose-Efficacy Relationships in Rat Spinal Cord Remyelination Models after Systemic Administration. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 339:519-529(2011).
Pepinsky, RB; Arndt, JW; et al. Structure of the LINGO-1-Anti-LINGO-1 Li81 Antibody Complex Provides Insights into the Biology of LINGO-1 and the Mechanism of Action of the Antibody Therapy. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 350:110-123(2014).