Magic™ Rabbit Anti-Human TPR Monoclonal antibody, clone 341524B5

Antibody Isotype

IgG

Clone

341524B5

Species Reactivity

Human

Immunogen

Peptide

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT795 - DMAB-CPT796
Cytometric Bead Array: 0.625-5 ng/mL

General Notes

This product (Catalog No. DMAB-CPT795) is a rabbit-derived monoclonal antibody raised against human TPR. It has been affinity purified by Protein A. Nucleoporin TPR was originally identified as the oncogenic activator of the met, raf, and trk protooncogenes. TPR is a large 270 kDa protein with a bipartite structure consisting of a ~1600-residue a-helical coiled-coil N-terminal domain and a highly acidic non-coiled ~800 amino acid carboxy terminus. TPR is localized exclusively to intranuclear filaments associated with the nucleoplasmic side of the NPC, by directly binding to Nup153.
DMAB-CPT795 is suitable for use in Cytometric Bead Array (0.625-5 ng/mL) application.
DMAB-CPT795 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

Nucleoprotein TPR; TPR; translocated promoter region

Entrez Gene ID

UniProt ID